Primary Training Faculty
(Endodontics) – modulation of inflammatory and neuropathic pain
(Cellular & Integrative Physiology) – Drosophila as a genetic model for neurodevelopmental and neurodegenerative disorders
(Pharmacology) – G protein - coupled receptors, signal transduction, ligand functional selectivity
(Cellular & Integrative Physiology) – molecular neuron-glia interactions, synaptic development and neurological disorders
(Pathology) – traumatic brain injury, neurodegenerative disorders, CTE
(Cancer Therapy and Research Center) – Neuro-oncology; overcoming resistance to cancer therapy driven by the hypoxic microenvironment
(Biochemistry and Structural Biology) - DNA repair and therapy resistance in glioblastoma
(Neurology) – hippocampal plasticity; mechanisms of neuronal hyperexcitability, epilepsy
(Physiology) – endocannabinoid signaling and neuroinflammation in neurodegenerative disease and TBI
(Cell Systems and Anatomy) – Genetic regulation of neuronal responses to aging and injury
(Molecular Medicine) – mammalian vision and retinal physiology
(Pharmacology) – molecular and cellular mechanisms of drug efficacy and differential signal transduction
(Pharmacology) – determinants of drug-seeking and drug-taking of abused substances, such as “bath salts”
(Cell Systems and Anatomy) – develop neural stem cells for therapeutic use in Parkinson’s and other diseases
(Cellular & Integrative Physiology) – regulation of monoamine transporters, psychotherapeutic drug effects
. (Endodontics) – Peripheral modulation of pain and inflammation; bioengineering and stem cells
(Pathology) – Use of human brain tissue to identify disease mechanisms, risk factors and protective factors for dementia
(Biochemistry and Structural Biology) – computational tools to study genetic and environmental factors in Alzheimer’s Disease and other neurodegenerative disorders
(Research Imaging Institute) – Non-invasive functional and structural neuroimaging in humans, non-human primates and rodents
(Pharmacology) – behavioral and pharmacological factors influencing the abuse liability of drugs
(Psychiatry) – neuroimaging to understand changes in brain function with psychotherapy for youth with PTSD
(Psychiatry) – Mechanisms of alcohol abuse and recovery; behavioral pharmacology of synthetic cannabinoids
(Neurology) – Brain injury and motor system recovery after stroke and cerebral amyloid angiopathy
(Cellular & Integrative Physiology) – serotonin and social behavior
(Biochemistry) –role of sulfatide and myelin lipids in the pathogenesis of Alzheimer’s Disease and aging
(Endodontics) – neuropharmacology of primary nociceptors and pain sensitivity
(Pharmacology) – genetic, cellular and molecular mechanisms of developmental neuropsychiatric disorders
(Pharmacology) – microglia and neuroinflammation in Alzheimer’s Disease; tau and calcium regulation
(Oral and Maxillofacial Surgery) – biochemical modulation of peripheral pain in nociceptive neurons by regulation of TRPV1 channel function
(Endodontics) - extracellular vesicles in pain; new diagnostics; pain management
(Oral & Maxillofacial Surgery) - regulation of sensory modalities including pain, itch, and gentle touch
(Biochemistry) - structural regulation of glutamate receptor function
(Cell Systems and Anatomy) – molecular and cellular regulation of neural stem cells and adult neurogenesis
(Cell Systems and Anatomy) – mitochondrial calcium regulation in cell death and survival in the aging process
(Cellular & Integrative Physiology) – ion channel dysregulation in mouse models of FXS and other developmental disorders
(Medicine) – Hematopoietic stem cell-derived macrophage gene therapy for neurodegenerative diseases
(Pharmacology) – Hippocampal and other afferent regulation of mesolimbic dopamine activity
(Pharmacology) – Functional genomics of neuropsychiatric and neurologic diseases; human iPS cell models
(Pharmacology) - Behavioral pharmacology; abuse potential of drugs; treatment of substance use disorders
(Pharmacology) – Effect of stress on behavior and brain function; novel therapeutics; cancer therapy-induced cognitive impairment
(Pharmacology) – Tryptophan metabolism and mechanisms linking neuroinflammation and depression
(Barshop Institute) – lipidomics; role of ceramides in Alzheimer’s Disease
(Cellular & Integrative Physiology) – Role of calcium signaling and neuron-astroglial interactions in neuromodulation and arousal
(Cellular & Integrative Physiology) – Axonal plasticity, cellular computation and signal processing in neural circuits
(Cell Systems and Anatomy) – role of mitochondrial oxidative stress in aging and Alzheimer’s Disease
(Endodontics) – Pain, analgesia, inflammation; Stem cells and regenerative endodontics in pain modulation
(Endodontics) – mechanisms and novel treatment approaches for oral cancer pain
(Biggs Inst.) – genetic mechanisms in Alzheimer’s Disease and other dementias
(Neurosurgery) – role of astrocyte lipoprotein metabolism in recovery from stroke and traumatic brain injury
(Cellular & Integrative Physiology) – ion channel physiology; regulation by intracellular signaling pathways and excitability
(Cellular & Integrative Physiology) – role of mTOR signaling in oligodendrocyte development and diseases of myelination
(Pharmacology) – neurodevelopment, cortical synapse and circuit formation, synaptogenesis
(Pharmacology) – role of catecholamines in aging; regulation of tyrosine hydroxylase gene expression
(Cell Systems & Anatomy) – computational biology, applying machine learning to gene network analysis
Affiliated Faculty
(Cell Systems and Anatomy) – mitochondrial deficits and mtDNA mutations in neurodegeneration and aging
(Pharmacology) – novel therapies for stress-related psychiatric disorders
(Medicine) – Cellular and molecular mechanisms of neutrophil signal transduction and activation; transcriptional regulation of genes relevant to biology of aging
(Cellular & Integrative Physiology) – pluripotent stem cells and regenerative medicine in neurodegenerative disease models
(Biochemistry and Structural Biology) – function and regulation of gap junctions; connexins in cell signaling and development
(Biochemistry and Structural Biology) – structure of gap junctions; genetic and structural diversity of connexins in disease
(Cell Systems and Anatomy) – RNA binding proteins and miRNA regulating gene expression in neuronal stress
(Neurology) – genetic, neuroimaging and behavioral aspects of epilepsy
(Ob/Gyn) – co-regulators of steroid and nuclear receptor signal transduction
(Cell Systems and Anatomy) – mechanisms of tumorigenesis and neural development in neurofibromatosis